Illustration of brain neurons affected by aging and the FTL1 protein.

'It is is truly a reversal': Scientists may have found how to stop brain ageing | BBC Science Focus Magazine | AI News Digest

Published: August 31, 2025, 8:07 p.m. Science Positive

Researchers at UC San Francisco have discovered a protein called FTL1 that plays a significant role in brain aging, particularly affecting the hippocampus. Their study revealed that older mice had higher levels of FTL1, leading to fewer neural connections and cognitive decline. Interestingly, reducing FTL1 levels in older mice restored their cognitive abilities and increased neural connections. This breakthrough suggests potential therapies to counteract the effects of aging on the brain. The findings, published in Nature Aging, offer hope for developing treatments that could alleviate age-related cognitive impairments.

brain agingFTL1 proteincognitive declineUCSF researchneuroscience